Bevacizumab use in breast cancer

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Avastin (chemical name: bevacizumab) is a targeted therapy that was approved by the U.S. Food and Drug Administration (FDA) in combination with Taxol (chemical name: paclitaxel) in February to treat people with metastatic HER2-negative breast cancer who haven't yet received chemotherapy for metastatic breast cancer.

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Nov 19, · Use of Avastin has already declined to 20 percent, from 60 percent, of American patients with newly diagnosed metastatic breast cancer, .

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Bevacizumab is a targeted therapy drug used to treat different types of cancer. It is best to read this information with our general information about the type of cancer you have. Bevacizumab .


Thus, substantial uncertainty remains over the best use of bevacizumab for metastatic breast cancer, which is reflected in the regulatory status of bevacizumab. European authorities have approved its use in first-line therapy for metastatic breast cancer, but the US Food and Drug Administration has not. This trial tested the effect of adding bevacizumab, a monoclonal antibody against vascular endothelial growth factor A, to paclitaxel for the initial treatment of metastatic breast cancer.
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Jun 29, · The Commissioner’s decision related to breast cancer will not affect Avastin’s approved indications for use in colon, lung, kidney, and brain cancers.

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Avastin (bevacizumab) is a cancer medicine that interferes with the growth and spread of cancer cells in the body. Avastin is used to treat a certain type of brain tumor, and certain types of cancers of the kidney, lung, colon, rectum, cervix, ovary, or fallopian tube. The specific indication that was revoked was for the use of bevacizumab in metastatic breast cancer, with paclitaxel for treatment of patients who have not received chemotherapy for metastatic HER2-negative breast cancer (US Food and Drug, ).

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Breast cancer approval. On March 28, , the European Commission approved bevacizumab in combination with paclitaxel for the first-line treatment of metastatic breast cancer. In , the FDA approved bevacizumab for use in breast cancer. A panel of outside advisers voted 5 to 4 against approval, but their recommendations were overruled. Donate Today. Your tax-deductible donation funds lifesaving research, treatment and Types: Cancer Basics, Cancer Prevention, Cancer Detection, Signs & Symptoms.

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Bevacizumab (Avastin®): Side Effects & Cancer .
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